With the rapid growth of ophthalmic products and the enforcement of the latest GMP regulations, the demand for higher aseptic standards in eye drop manufacturing has never been greater. Among all production steps, the filling and sealing process plays a decisive role in safeguarding drug quality and ensuring manufacturing efficiency.

Leveraging deep technical expertise and the resources of our European R\&D center, Truking has developed a multidose ophthalmic filling & sealing solution tailored to the latest GMP requirements. This solution integrates intelligent automation, aseptic design, and precision control to help pharmaceutical manufacturers achieve both compliance and operational excellence.

1. HighSpeed Intelligent Bottle Unscrambling

-Singlehopper dualchannel feeding enables highfrequency bottle conveying with over 4× speed improvement compared to conventional systems.

-Precise orientation detection distinguishes upright vs. inverted bottles via dualposition sensing, followed by automatic correction.

-Servodriven flipping & dual rotary conveyors synchronize bottle movement, avoiding friction, scratches, or particle generation, supporting speeds of 200+ pcs/min.

-Automatic rejection of inverted bottles ensures stability and reliability.

-Fully compliant with FDA & GMP requirements: quickdisassembly design, sterile contact components, laminar flow–friendly structure, and particlefree conveying.

2. Advanced Sterile Bottle Cleaning

-Static elimination with ionized air ensures stable particle removal from bottle surfaces.

-Closed blowvacuum cleaning: sterile filtered air enters the bottle interior while vacuum simultaneously extracts particles, avoiding contamination to the Grade A environment.

-Online SIP functionality simplifies operations by eliminating offline sterilization, reducing contamination risk, and lowering operator dependency.

3. FullServo Intelligent Capping System

-Closedloop torque control allows precise adjustment of capping force through HMI settings.

-Highprecision pneumatic clamping ensures stable performance and high cap qualification rates.

-Torque traceability: every bottle’s torque data is recorded and archived, providing a complete digital record for quality assurance.

4. 100% InProcess Control (IPC) RealTime Monitoring

-Integrated weighing modules with vibration isolation ensure accurate measurement even under laminar flow, static, or vibration interference.

-Dynamic compensation algorithms correct deviations in real time.

-100% online weighing detection during production guarantees dosage accuracy and consistency.

-Automatic calibration and pump testing before production further enhance reliability, with complete batch data stored for traceability.

5. Linear Layout Optimized for Aseptic Production

-Straightline configuration and flattened design minimize particle retention and simplify laminar flow.

-Ergonomic access with working zones within 550mm of the edge ensures ease of operation.

-Perfectly suited for isolator and ORABS environments, enabling robust aseptic protection.

By integrating speed, precision, and compliance into one comprehensive solution, Truking’s ophthalmic filling & sealing technology helps manufacturers safeguard product quality, meet stringent regulations, and improve production efficiency.

As ophthalmic markets continue to expand, Truking remains committed to delivering intelligent, aseptic, and traceable solutions that empower pharmaceutical companies to navigate new challenges with confidence.